Terumo Cardiovascular Group

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Infection Control

Platelet Therapy

Information provided on this website is not intended to make claims that the products are safe and effective for any use other than those explicitly described in the Instructions for Use. Clinicians should refer to the Instructions for Use or Owner's Manuals for complete information on the intended use of any product mentioned in this website.

STUDY OVERVIEW: Autologous Platelet Gel Increases Tissue Phagocytic Capacity 2.5x in Diabetic Cardiac Surgery Patients
Dr. Gunaydin describes the importance of conducting a biomaterial evaluation to determine the mechanism by which platelet gel protects against sternal wound infection. (links to related publications)

STUDY: Cost Advantages Using Autologous Platelet Gel
An interview with Randy Brown, MD, Southeast Missouri Hospital. After a two-year study using platelet gel, the team lowered costs by reducing the need for expensive surgical glues, and eliminated costs associated with mediastinitis.

POSTER ABSTRACT: Autologous Platelet Gel for the Prevention of Sternal Wound Infection in Diabetic Patients Undergoing Bilateral Thoracic Artery Grafting. Gunaydin S et al. 45th Annual Meeting of the Society of Thoracic Surgeons 2009, San Francisco.
In the first STS presentation on the subject, the authors conclude that platelet gel seems to protect diabetic cardiac surgery patients against infection via growth factors and phagocytic capcity.

ABSTRACT: Clinical Impact and Biomaterial Evaluation of Autologous Platelet Gel in Cardiac Surgery. Perfusion 2008; 23: 179-186. Gunaydin S et al.
In a prospective, randomized, 64-patient study, the authors determine that autologous platelet gel was superior to gelatine in its effects on hemostasis, wound healing, and resistance to infection.

ABSTRACT: The Use of Autologous Platelet Gel to Treat Difficult-to-Heal-Wounds: A Pilot Study. Transfusion Practice 2004;44. Mazzucco, et al.
This study evaluated the use of PRP to heal sternal wounds and necrotic ulcers and found patients with dehiscent sternal wounds achieved 100% healing in half the time.